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Drexler, “Pilocarpine-induced shift of an accommodating intraocular lens: AT-45 Crystalens,” J.

Kochevar, “Photochemical keratodesmos for bonding corneal incisions,” Invest.

Presbyopia, the age-related loss of the crystalline lens’s ability to dynamically focus, occurs primarily because of stiffening of lens material, making the ciliary muscle forces insufficient to reshape the lens.

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Srinivasan, “Fibrin glue-assisted sutureless posterior chamber intraocular lens implantation in eyes with deficient posterior capsules,” J.

Holden, “Optomechanical response of human and monkey lenses in a stretcher,” Invest.

Refer to the Directions for Use labeling for a complete listing of indications, warnings and precautions, clinical trial information, etc.

Federal (USA) law restricts this device to the sale by or on the order of a physician.

Unlike most other IOLs, the AO IOL optic has hinges connecting it to the haptic; please see adverse events section below for more information.

Do not resterilize this intraocular lens by any method.Here we present a novel accommodating intraocular lens (AIOL) able to reshape upon equatorial forces in compliance with the eye’s accommodating mechanism. The concept and design parameters are demonstrated through finite element model simulations and measurements in a manufactured AIOL prototype, using custom quantitative 3D OCT (geometrical changes) and laser ray tracing (power changes), with forces radially applied using a custom eight-arm mechanical stretcher. Physicians should consider the characteristics of each individual vaulting case prior to determining the appropriate treatment.Data on long-term follow-up after treatment of vaulting is not available.AO IOL delivers an active range of vision, excellent contrast sensitivity, and minimized issues with halos and glare across a range of vision that includes functional near, intermediate, and distance vision.

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