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Multiplicity of gamete types within a species would still be considered a form of sexual reproduction.However, no third gamete type is known in multicellular plants or animals.

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Disregarding intermediates, the basic distinction between asexual and sexual reproduction is the way in which the genetic material is processed.

Typically, prior to an asexual division, a cell duplicates its genetic information content, and then divides. In sexual reproduction, there are special kinds of cells that divide without prior duplication of its genetic material, in a process named meiosis.

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Many species, both plants and animals, have sexual specialization, and their populations are divided into male and female individuals.

Conversely, there are also species in which there is no sexual specialization, and the same individuals both contain masculine and feminine reproductive organs, and they are called hermaphrodites. The reason for the evolution of sex, and the reason(s) it has survived to the present, are still matters of debate.

For instance, mate choice and sexual selection can accelerate the evolution of physical differences between the sexes.

Among humans and other mammals, males typically carry an X and a Y chromosome (XY), whereas females typically carry two X chromosomes (XX), which are a part of the XY sex-determination system. Other animals have different sex-determination systems, such as the ZW system in birds, the X0 system in insects, and various environmental systems, for example in crustaceans.

Some bacteria use conjugation to transfer genetic material between cells; while not the same as sexual reproduction, this also results in the mixture of genetic traits.

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